C-reactive Protein Levels Among Individuals With COVID-19

Completed

• Conditions: Coronavirus Infection
• Interventions: Diagnostic Test: C-reactive protein

• Registration Number: NCT04373798
• Lead Sponsor: Henning Bliddal

Brief Summary

The primary objective of this multi-center study is to clarify the value of a CRP measurement for triage of patients initially presenting with light symptoms of the COVID-19 infection.

Current recommendations of management of COVID-19 include large-scale tests for virus. Such tests reveal whether an individual is infected with the virus, however, the demonstration of virus per se has no prognostic value for the ensuing course of the COVID-19 disease. Publications of possible treatments strategies increase exponentially, while evidence of triage of the affected individuals is mainly based on the level of pulmonary affection as measured by the Oxygen saturation.

To inform decision making for which patients are to be hospitalized due to risk of developing more severe affection, this study addresses the question, whether triage may be performed with the aid of a simple CRP measurement.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-05-01
• Study First Submitted QC: 2020-05-01
• Study Start: 2020-05-04
• Study First Posted: 2020-05-04
• Primary Completion: 2020-08-30
• Study Completion: 2021-03-30
• Status Verified: 2021-08
• Last Update Submitted: 2021-08-17
• Last Update Posted: 2021-08-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1006

Inclusion Criteria

1. A test for COVID-19 taken at the check point
2. Signed, informed consent for blood test to be drawn for the Biobank

Exclusion Criteria

1. Former admission to hospital for COVID-19
2. Direct admission from check point.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Suspected COVID-19	C-reactive protein	Individuals with symptoms who are seen at covid19 check points for covid19 diagnosis.

Primary Outcome Measures

Name	Time	Method
Hospitalisation	within 28 days	Admission to a hospital. Reason for admission is recorded.

Secondary Outcome Measures

Name	Time	Method
Death	within 28 days
Transfer to Intensive Care Unit	within 28 days
Oxygen treatment during hospitalisation	within 28 days

Trial Locations

Locations (1)

The Parker Institute, Frederiksberg Hospital; 🇩🇰 Copenhagen, Denmark