The ADDFAM study: Realising the potential of the family history in risk assessment and primary prevention of Coronary Heart Disease (CHD) in primary care

Not Applicable

Completed

• Conditions: Coronary Heart Disease (CHD); Circulatory System; Heart Disease

• Registration Number: ISRCTN17943542
• Lead Sponsor: niversity of Nottingham (UK)

Brief Summary

1. 2009 study protocol in http://www.ncbi.nlm.nih.gov/pubmed/19821989 2. 2012 results in http://www.ncbi.nlm.nih.gov/pubmed/22351711

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-10-08
• Study Completion: 2009-04-02
• Last Update Posted: 12 February 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1400

Inclusion Criteria

Practices: To be within either Trent Primary Care Trusts (PCTs) in East Midlands or PCTs in Central Cornwall, Plymouth and Exeter
Participants: To be registered patients at the above practices and be between 30 and 65 years of age; Practices: To be within either Trent Primary Care Trusts (PCTs) in East Midlands or PCTs in Central Cornwall, Plymouth and Exeter
Participants: To be registered patients at the above practices and be between 30 and 65 years of age

Exclusion Criteria

General Practices outside of these defined areas will be excluded

Participants exclusion criteria:
1. Patients noted to have a previous history of atherosclerotic disease (this includes CHD, CerebroVascular Accident [CVA] and peripheral vascular disease)
2. Previous history of diabetes mellitus
3. Patients already on statin therapy or other lipid lowering medication
4. Patients considered by the General Practitioners to be inappropriate to recruit due to psychosocial reasons; General Practices outside of these defined areas will be excluded

Participants exclusion criteria:
1. Patients noted to have a previous history of atherosclerotic disease (this includes CHD, CerebroVascular Accident [CVA] and peripheral vascular disease)
2. Previous history of diabetes mellitus
3. Patients already on statin therapy or other lipid lowering medication
4. Patients considered by the General Practitioners to be inappropriate to recruit due to psychosocial reasons

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The increase in the proportion of patients falling in the high risk group resulting from the inclusion of family history in the CHD risk assessment.;The increase in the proportion of patients falling in the high risk group resulting from the inclusion of family history in the CHD risk assessment.