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临床试验/CTRI/2025/12/098795
CTRI/2025/12/098795尚未招募Unknown

Comparison Of Nebulized Dexmedetomidine Plus Lidocaine Combination Versus Nebulized Dexmedetomidine Alone For Awake Fiberoptic Nasotracheal Intubation A Prospective Randomized Controlled Study

Pradipta Laha1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2025年12月25日最近更新:

试验速览

阶段
Unknown
状态
尚未招募
发起方
入组人数
88
试验地点
1

研究概览

简要总结

This Prospective Randomized controlled study is the comparison of nebulized dexmedetomidine plus lidocaine versus dexmedetomidine alone in awake nasotracheal fiberoptic intubation. The place of study is Command Hospital Eastern Command  a tertiary care teaching hospital in Kolkata . The total duration of the study is 16 months.  Total Number of participants in the study is 88. The inclusion criteria of the study are age between 18 to 65 years with ASA physical status I to II who are scheduled for elective surgery under general anaesthesia. The participants will be divided into two groups 44 in each. Group DL will receive nebulized dexmedetomidine combined with lidocaine and group DN will receive nebulized dexmedetomidine with normal saline which will be administered 20 minutes prior to awake fiberoptic intubation. Premedication will be given in both the groups. The primary objective is to compare the time required for awake fiberoptic nasotracheal intubation between the two groups. The secondary objectives of this study is to assess the ease and quality of awake fiberoptic nasotracheal intubation. This study aims to evaluate whether the addition of nebulized lidocaine improves the outcome compared to nebulized dexmedetomidine alone during awake fiberoptic nasotracheal intubation. The study is a double blinded study where the participants and professional performing the procedure will be blinded. Randomization will be done by sealed opaque envelopes.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • ASA Physical Status I-II Schedule For Elective Surgery Under General Anaesthesia With AFOI Informed Written Consent.

排除标准

  • Patient Unwilling To Participate Nasal Obstruction Polyps Bleeding Disorders Allergy To Lidocaine Or Dexmedetomidine Pregnant Women.

研究者

发起方
Pradipta Laha
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Pradipta Laha

Command Hospital Eastern Command

研究点 (1)

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