NCT03170180已完成2 期
Exploratory Study of Drug Sensitivity Prediction Software (IRCR-DReSS) With Patient-derived Tumor Cells of Metastatic Gastric Cancer
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- response rate
研究概览
简要总结
- Metastatic gastric cancer patients who failed standard treatment will be enrolled in this study.
- After consent form, patient-derived cancer cell will be collected and tested with 3 kinds of drugs (sunitinib, gefitinib, imatinib).
- Drug sensitivity prediction software (IRCR-DReSS) will present level of sensitivity and patients will be treated with sensitive drugs.
- Patients will be evaluated every 6 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •metastatic gastric cancer
- •life expectancy >-3 months
- •ascites and pleural effusion that can be drained
- •Proper organ function
- •Patients who will be enrolled in sunitinib, gefitinib, imatinib clinical trial
排除标准
- •HBeAg, HCV, HIV (+)
- •Active infection
- •Uncontrolled systemic disease
研究组 & 干预措施
sunitinib
Experimental
干预措施: Sunitinib (Drug)
gefitinib
Experimental
干预措施: Gefitinib (Drug)
imatinib
Experimental
干预措施: Imatinib (Drug)
结局指标
主要结局
response rate
时间窗: 2 years
次要结局
未报告次要终点
研究者
Jeeyun Lee
Professor
Samsung Medical Center
研究点 (1)
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