Additive effects of yoga in women with polycystic ovary syndrome (PCOS) with infertility
Not Applicable
- Conditions
- Health Condition 1: E282- Polycystic ovarian syndrome
- Registration Number
- CTRI/2023/02/049824
- Lead Sponsor
- All India Institute of Medical Sciences, New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Infertile PCOS women diagnosed according to modified Rotterdam criteria will be recruited for the study.
Exclusion Criteria
1. Patient with history of endometriosis
2. Patient with diminished ovarian reserve (AMH <1.5 ng/ml, AFC <7, FSH >10 IU/ml)
3. Patient is on any contraception or insulin treatment within last 3 months of recruitment
4. Patient with uncontrolled thyroid/prolactin disorder.
5. Patient with non-classical congenital adrenal hyperplasia
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Follicular response (dominant follicle â?¥17mm) among women getting yoga therapy in addition to <br/ ><br>ovulation induction cycles among infertile PCOS womenTimepoint: Follicular response (dominant follicle â?¥17mm) among women getting yoga therapy in addition to <br/ ><br>ovulation induction cycles among infertile PCOS women at baseline, 6 weeks and 12 weeks.
- Secondary Outcome Measures
Name Time Method Clinical parameters ( BMI, waist circumference (WC),waist hip ratio (WHR), neck circumference <br/ ><br>(NC) <br/ ><br>â?¢ Metabolic parameters ( HOMA-IR, Lipid profile) <br/ ><br>â?¢ Endocrine parameters (LH/FSH ratio, AMH, SHBG, testosterone)Timepoint: AT baseline; 3 months and 6 months;Duration of stimulation to achieve target follicular response <br/ ><br>â?¢ Clinical pregnancy rate (documented viable pregnancy on USG) <br/ ><br>â?¢ Ongoing pregnancy rate <br/ ><br>â?¢ Live birth rateTimepoint: During ovulation induction cycles monitoring;To evaluate the effect of yoga on following parameters: <br/ ><br>â?¢ Need to add gonadotrophins to ovarian stimulation <br/ ><br>â?¢Timepoint: during ovulation induction cycles