Clinical study on anti-atherosclerotic effect of azelnidipine/amlodipine in the hypertensive patients with type 2 diabetes
Not Applicable
- Conditions
- Hypertension
- Registration Number
- JPRN-UMIN000000495
- Lead Sponsor
- Advanced Medicine Study Group in Kyushu Island
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
Not provided
Exclusion Criteria
1. Patients using insulin 2. Patients with secondary hypertension 3. Patients on hemodialysis 4. Pregnant women or those who plan pregnancy 5. Patients with history of hypersensitivity to olmesartan, azelnizipine, amlodipine 6. Patients with severe liver injury 7. Patients with severe renal failure (serum CRE>=3.0mg/dl) 8. Other patients judged unsuitable for the study by investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fasting plasma glucose, insulin HbA1c T-Chol, HDL-C, LDL-C, TG hs-CRP, HM-adiponectine nitrotyrosine, urinary 8-isoprostan
- Secondary Outcome Measures
Name Time Method home or clinic blood pressure