Extra local pain relief in total knee arthroplasty
- Conditions
- ocal infiltration analgesia (LIA) a multimodal pain management strategy in total knee arthroplasty.This study will investigate the effect of LIA on postoperative pain, opiod consumption, length of hospital stay and adverse effects.By downscaling the LIA it's hypotised there will be less adverse effects and no differences in other endpoints.Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
- Registration Number
- EUCTR2012-001432-62-NL
- Lead Sponsor
- Reinier de Graaf Groep
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- Not specified
The hospital criteria and protocol for patients who are diagnosed for a total knee arthroplasty in the outpatients’ clinic of the Orthopaedic Department of RdGG Hospital Delft
• Patients at least 18 years of age
• Scheduled for elective total knee arthroplasty
• ASA I-III
• Willing to participate
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 90
• age < 18
• ASA > III
• moderate or severe cardiac disease, bronchial asthma
• allergy against Ropivacain, Gabapentin
• pregnancy
• severe psychiatric disease
• moderate to severe dementia, mentally retarded
• BMI > 40
• Abuse alcohol and drugs
• Chronic use of opioids
• Patients diagnosed Rheumatoid arthritis
• Revision TKA
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method