The prevalence of bile acid diarrhéa and the effect of budesonid on the bile acid homeostasis in patients with microscopic colitis

Zealand University Hospital0 个研究点目标入组 54 人开始时间: 2019年7月25日最近更新: 2023年10月3日

适应症

试验速览

暂无简介。

•Suspected activity in MC, defined by Hjortswang criteria: 3 stools daily OR one watery (Bristol type 6or7) stools daily, as a mean over the last 6-7 days.
•Proven microscopic colitis (collagenous, lymphocytic or incomplete) in biopsies from the last 6 years
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 25
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 29

•Age < 18 years
•Intestinal resection other than appendectomy
•cholecystectomy
•Other chronic intestinal disease with diarrhoea
•Use of other constipation agent than loperamide
•Systemic treatment with steroid within 2 weeks of the start of treatment
•Suspected or proven gastrointestinal infection
•Allergy to budesonide
•Lack of compliance or understanding of the trial
•If taking statin or fibrate therapy: unwilling to pause medical treatment against hypercholesterolaemia

发起方