Risk Prediction System for Metabolic Associated Fatty Liver Disease, a Community-based Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 8,103
- 试验地点
- 1
- 主要终点
- Cardiovascular disease
研究概览
简要总结
Metabolic associated fatty liver disease(MEFLD) is a major chronic liver disease that can lead to various adverse events, such as liver cancer, cardiovascular disease, and chronic kidney disease. The present community-based cohort study enrolls subjects who take health physical examinations at the sub-center outpatient department, Beijing Friendship Hospital. Investigators collect their baseline information, including demographic data, clinical history, physical examination, laboratory results, imageological examination, and so on. Follow-up surveys are conducted annually and the information collected is the same as the baseline. The outcome information, including cardiovascular disease, malignancy, liver cirrhosis, liver decompensation, liver transplantation, and all-cause mortality, are obtained by linking to the hospital discharge database and death registration system of Beijing. The primary aim of the study is to build a risk-stratified evaluation system for MAFLD through the cohort.
详细描述
The present community-based cohort study enrolls subjects who take physical health examinations at the sub-center outpatient department, Beijing Friendship Hospital. After signing the informed consent, Their previous health physical examination results, which were recorded in the Hospital Information System (HIS) are collected retrospectively. Then, Investigators collect their baseline information, including demographic data, clinical history, physical examination, laboratory results, image logical examination, and so on. Additionally, follow-up surveys will be conducted annually and the information collected is the same as the baseline. The outcome information, including cardiovascular disease, malignancy, liver cirrhosis, liver decompensation, liver transplantation, and all-cause mortality, is obtained from the hospital discharge database and death registration system in Beijing. The study's primary aim is to build a risk-stratified evaluation system for MAFLD through a community population cohort with long-term stable follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18 years or older
- •Permanent residents in Beijing
- •Signing informed consent
排除标准
- 未提供
结局指标
主要结局
Cardiovascular disease
时间窗: 1 to 10 years
Incidence of cardiovascular disease during follow-ups
次要结局
- All-cause mortality(1 to 10 years)
- Malignancy(1 to 10 years)
- Liver cirrhosis(1 to 10 years)
- Liver decompensation(1 to 10 years)
- Liver transplantation(1 to 10 years)
