CTIS2023-508824-36-00进行中（未招募）1 期
QUANTITATIVE RENAL HYPERPOLARIZED [1-13C]PYRUVATE PERFUSION AND METABOLIC IMAGING IN DIABETIC KIDNEY DISEASE
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 27
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 65+（—）
- 性别
- All
入选标准
- •All participants: Aged 18 – 85 years and pre-menopausal women must be confirmed non-pregnant., Type 1 Diabetes Mellitus with diabetic kidney disease: eGFR < 60 ml/min andmacroalbuminuria (urine albumin-creatinine ratio > 300 mg/g), Type 1 diabetes mellitus without diabetic kidney disease: eGFR > 60 ml/min and no albuminuria (urine albumin-creatinine ratio < 30 mg/g) and No signs of proliferative retinopathy or macular edema.
排除标准
- •Contraindications for MRI: Significant cardiac disease, Obstructive lung disease, pacemaker, neurostimulator, cholera implant, metal foreign bodies, claustrophobia, largest circumference including arms > 160 cm., Competing systemic diseases, eGFR<30 ml/min, Stents or other devices implanted close to the kidneys that may cause imaging artifacts, Pyruvate Allergy
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