Mortality Reduction in Septic Shock by Plasma Adsorption
- Conditions
- Septic Shock
- Registration Number
- NCT02357433
- Lead Sponsor
- Francisco Colomina Climent
- Brief Summary
The study objective is to clarify whether the application of high doses CPFA (Coupled Plasma-Filtration Adsorption) in addition to the current clinical practice is able to reduce hospital mortality in septic shock patients in intensive care unit (ICU).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 55
- all patients admitted to the ICU in septic shock
- all patients that develop septic shock while in the ICU
- Age less than 18 years
- Pregnancy
- Estimated life expectancy (due to comorbidities) less than 90 days
- Presence of relative or absolute contraindications to CPFA
- Absence of informed consen
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Hospital mortality 28 days
- Secondary Outcome Measures
Name Time Method time resolution of septic shock within the first 28 days normalization of lactate, and the decrease in vasoactive drugs
Trial Locations
- Locations (10)
Hospital de Vinalopó
🇪🇸Elche, Alicante, Spain
Hospital de la Vega Baja
🇪🇸Orihuela, Alicante, Spain
Hospital Universitario de San Juan de Alicante
🇪🇸Sant Joan d'Alacant, Alicante, Spain
Hospital de Torrevieja
🇪🇸Torrevieja, Alicante, Spain
Hospital Marina Baixa
🇪🇸Villajoyosa, Alicante, Spain
Hospital de la Plana
🇪🇸Villarreal, Castellon, Spain
Hospital General Universitario de Santa Lucia
🇪🇸Cartagena, Murcia, Spain
Hospital Frances De Borja de Gandia
🇪🇸Gandia, Valencia, Spain
Hospital Lluis Alcanyis
🇪🇸Xátiva, Valencia, Spain
Hospital General Universitario de Alicante
🇪🇸Alicante, Spain
Hospital de Vinalopó🇪🇸Elche, Alicante, Spain