Hysteroscopic Findings in Ovarian Polycystic and Unexplained Infertile Women.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- endometrial findings in polycystic and unexplained infertile women
研究概览
简要总结
In many PCO infertile patients, abnormal endometrial echogenicity and thickness are documented by TVS and proved by endometrial biopsy in some cases. Should patients with normal appearance of the endometrium (echogenicity and thickness) by TVS require, endometrial biopsy remains controversial.
Therefore, if hysteroscopic examination demonstrates the endometrial pattern (echogenicity, vascularity, and thickness) in different PCO cases and correlates it to TVS and histopathology, this would recommend abstinence of endometrial curettage in some PCO patients.
详细描述
Aim of the work The study aimed to evaluate post menstrual hysteroscopic findings in ovarian PCO and unexplained infertility and correlate them with TVS findings and final histopathologic diagnosis.
Methodology:
- Study design:
A cross-sectional study. 2. Setting: Infertility out-patient clinic, Outpatient ultrasonography unit and office hysteroscopy unit of the WWoman'sHealth University Hospital Assiut University. 3. Patients:
Infertile women in the reproductive age group (18-40 years) whether 1ry or 2ry. 4. Grouping: it will include two groups of infertile women. Group A will consist of 100 PCO infertile women, while group B will consist of 50-unexplained infertility.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Reproductive age (18-40).
- •Infertility: 1ry or 2ry.
- •No contraindication for hysteroscopy or histopathology. e.g severe bleeding cervical stenosis.
- •Postmenstrual.
排除标准
- •contraindication for hysteroscopy or histopathology. e.g severe bleeding cervical stenosis.
- •Non infertility.
- •Adolescents and virgins.
结局指标
主要结局
endometrial findings in polycystic and unexplained infertile women
时间窗: 1 year
office hysteroscopy to assess endometrial thickness vascularity or any abnormal pathology.
次要结局
- Access to Darwish hysteroscopic triad (DHT)(1 year)
研究者
Professor Atef Darwish
Professor of Obstetrics and Gynecology
Woman's Health University Hospital, Egypt