Yorkshire kidney screening trial

Not Applicable

Completed

Conditions: Cancer
Screening for renal cell carcinoma (RCC) in participants of the Yorkshire Lung Screening Trial

Registration Number: ISRCTN18055040

Lead Sponsor: niversity of Leeds

Brief Summary: 2022 Protocol article in https://pubmed.ncbi.nlm.nih.gov/36127097/ (added 27/09/2022)

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 4019

Inclusion Criteria

The study is only open to participants of the Yorkshire Lung Screening Trial who are high risk for lung cancer as defined by one of the three criteria:
1. 30 pack year history of smoking and current smoker or quit within the last 15 years (USPSTF criteria)
2, Lung cancer risk of =1.51% over 6 years as calculated by the PLCOM2012 score
3. Lung cancer risk of =5% over 5 years as calculated by the LLPv2. score)

Exclusion Criteria

1. Have undergone CT Thorax within the previous 12 months
2. Unable to provide informed consent to study
3. Unable to have a chest or abdominal non-contrast CT scan
4. Previous diagnosis of kidney cancer
5. Have undergone abdominal CT scan in previous 6 months

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.The proportion of individuals attending the T2 round of YLST who take up the offer of an abdominal CT scan measured using patient records, reports and study visit logs. Calculated at a single time point2. The acceptability to participants of combined lung and RCC screening by non-contrast CT scanning measured using interviews within 3 months of the invitation to the study3. The acceptability to healthcare professionals involved in the screening of combining RCC screening by non-contrast CT scanning with lung cancer screening measured using interviews within 6 months of study start4, The additional time required for the combined screening approach, including the time to provide information, consent participants, and perform the lengthier CT scan, the time needed by radiologists for reporting the CT scans, and the additional time to review abdominal CT findings measured using timing sheets at a single time point

Secondary Outcome Measures