Symptom relief of gastric acid suppressants in patients with reflux esophagitis - Randomized controlled comparative study of vonoprazan and esomeprazole
Not Applicable
Recruiting
- Conditions
- Reflex esophagitis patients
- Registration Number
- JPRN-UMIN000026250
- Lead Sponsor
- Hirano Gastroenterology Clinic
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1:Patients with warning signs such as vomiting, gastrointestinal bleeding and sudden weight loss. 2:Patients with confirmed or suspected malignant diseases. 3:Patients with a history of gastrointestinal resection of vagotomy. 4:Patients with a history of irritable bowel syndrome. 5:Patients whose participation in this study would be contraindicated due to complications such as serious hepatic, renal or heart disease. 6:Pregnant patients, possibly pregnant or lactating women. 7:Patients judged as inadequate in participation of this study by their attending physicians.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sufficient relief of GERD symptom Change of total score of heartburn and regurgitation evaluated by GOS Questionnaire after 4,8-week treatment
- Secondary Outcome Measures
Name Time Method 1:The Change of individual score and the improvement of symptom (heartburn, regurgitation) evaluated using GOS /FSSG after 4,8-week treatment 2:The improvement of symptom (epigastric pain, nausea, vomiting) evaluated using GOS /FSSG after 4,8-week treatment 3:Treatment response evaluated by GOS /FSSG after 4,8-week treatment