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Molecular Markers in Cervical Cancer Screening in the Feasibility of the Mathematical Markov Model Analysis

Conditions
Cervical Cancer
Registration Number
NCT00889902
Lead Sponsor
Wuhan University
Brief Summary

The purpose of this study is to:

1. make p16INK4A as a cervical cancer screening of tumor markers, cytology improve existing diagnostic sensitivity, specificity, repeatability and validity, so as to effectively prompted the early discovery and diagnosis of cervical cancer.

2. reduce screening costs, screening and benefits into quantitative evaluation, for our country to develop cervical cancer prevention and control strategy to provide a reliable theoretical basis.

Detailed Description

1. To carry out large-scale prospective randomized controlled clinical study to evaluate the "cytological molecular markers Detect + P16INK4A" methods of screening accuracy and reliability, as well as the screening method of the biological effects.

2. Markov set up mathematical model of screening tests to quantify the inputs and the evaluation proceeds. With a view to optimize and perfect a simple, convenient, practical and efficient program of cervical cancer screening.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
200
Inclusion Criteria
  • Married women aged 25 to 65-year-old with risk factors
  • No tumor and pelvic radiation therapy history
  • Non-pregnant women at present
Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

People'S Hospital

🇨🇳

Wufeng county, Hubei, China

People'S Hospital
🇨🇳Wufeng county, Hubei, China

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