Novel Method for Diagnosing Lateral Patellar Compression Syndrome Using X-ray: a Retrospective Case-Control Study

Completed

• Conditions: Lateral Patellar Compression Syndrome
• Interventions: Other: no intervention

• Registration Number: NCT04454593
• Lead Sponsor: Peking University Third Hospital

Brief Summary

This study evaluates whether the patellar axial radiograph of lateral patellar curvature angle （LPCA）with knee flexion at 30 ° can be used as a new diagnostic surrogate of lateral patellar compression syndrome（LPCS）. We believe that the new index LPCA has high sensitivity and specificity in initial diagnosis of LPCS using axial patellar radiograph with knee flexion at 30 ° , and has high application value.

Detailed Description

Background: A well-established reference is lacking for diagnosing lateral patellar compression syndrome (LPCS), and this diagnosis currently depends on clinicians' subjective judgment and several examination results. X-rays are primarily used to diagnose LPCS, but they have low detection rates of patellar tilt using the congruence angle (CA) and patellar tilting angle (PTA).

Purpose: To investigate whether patellar axial radiography of the lateral patellar curvature angle (LPCA) of knee in 30° flexion can diagnose LPCS.

Methods: We enrolled 87 patients between 2016 and 2019 and divided them as per diagnosis into three groups of 29 each: LPCS, patellar dislocation (PD, control), and meniscus tear (MT, negative control) groups. A senior radiologist and the chief physician of sports medicine examined their patellar axial radiographs of the knee in 30° flexion using a computer imaging system, measuring LPCA, PTA, and CA. Univariate analysis of variance and Kruskal-Wallis H test were used to compare measurement data with normal distribution and non-normal distribution, respectively. Bonferroni correction was used to analyze different indicators for different groups. The area under the curve (AUC) was calculated to verify the value of LPCA in initial diagnosis of LPCS.

Study Timeline

• Study Start: 2020-03-22
• Primary Completion: 2020-04-22
• Study Completion: 2020-05-22
• Status Verified: 2020-06
• Study First Submitted: 2020-06-29
• Study First Submitted QC: 2020-06-30
• Last Update Submitted: 2020-06-30
• Study First Posted: 2020-07-01
• Last Update Posted: 2020-07-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 87

Inclusion Criteria

• Patients were diagnosed as LPCS ，MT and PD respectively

Read More

Exclusion Criteria

• patients with ligament injury, malunion of patella fracture, free bodies in the joint, surgical contraindications, and with both knees affected.

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
meniscus tear	no intervention	Patients diagnosed with meniscus tear between February 2016 and April 2019
patellar dislocation	no intervention	Patients diagnosed with patellar dislocation between February 2016 and April 2019
Lateral patellar compression syndrome	no intervention	Patients diagnosed with lateral patellar compression syndrome between February 2016 and April 2019

Primary Outcome Measures

Name	Time	Method
lateral patellar curvature angle	between 2016 and 2019	lateral patellar curvature angle in three groups was compared

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China