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Intensive Language-Action Therapy (ILAT): How does high training intensity affect speech and language recovery in stroke patients with chronic aphasia?

Not Applicable
Conditions
F80.1
Expressive language disorder
Registration Number
DRKS00007829
Lead Sponsor
Freie Universität Berlin Brain Language Laboratory
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Patients are able to give informed consent;

diagnosis of aphasia;

patients are more than one year post-infarction;

German native speakers;

no visual or auditory impairments

Exclusion Criteria

severe visual or auditory impairments;

severe apraxia of speech or agnosia;

reinfarctions;

additional neurological disorders

major depression or psychosis

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Standardized aphasia battery: Aachen Aphasia Test (AAT), performed at four different points in time:<br><br>(T0) 2 weeks before the onset of the treatment<br><br>(T1) 1 day prior to the onset of the treatment<br><br>(T2) 2 weeks after the onset of the treatment<br><br>(T3) 4 weeks after the onset of the treatment (end of therapy)
Secondary Outcome Measures
NameTimeMethod
Questionnaires:<br>Motivation;<br>Beck's Depression Inventory (BDI);<br>Selbstwirksamkeitserwartung (SWE);<br>Fragebogen zur Sozialen Unterstützung (FSozU);<br>Montgomery-Åsberg Depression Rating Scale (MADRS);<br>Activities of Daily Living (ADL);<br>Communication Activity Log (CAL)<br><br>Communicative-pragmatic request and naming task:<br>Action Communication Test (ACT)<br><br>IQ assessment:<br>Raven's Standard Progressive Matrices (SPM)<br><br>EEG:<br>Lexical decision task and oddball paradigm; dependent variables: event-related potentials, error rates, reaction times<br><br>fMRI:<br>Lexical decision task; dependent variables: event-related potentials, error rates, reaction times<br><br>Each clinical variable is assessed at four different points in time (T0, T1, T2, T3; see above).
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