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Clinical Trials/CTRI/2024/12/078557
CTRI/2024/12/078557
Not yet recruiting
Phase 2/3

Single arm clinical study to assess the effect of bhumyamalaki kwath in mutrakruchhra with special reference to urine routine and microscopic examination

Dr Jyotsna Raghunath Payamal1 site in 1 country60 target enrollmentStarted: January 10, 2025Last updated:

Overview

Phase
Phase 2/3
Status
Not yet recruiting
Sponsor
Dr Jyotsna Raghunath Payamal
Enrollment
60
Locations
1
Primary Endpoint
To study the effect of bhumyamalaki kwath in mutrakruchhra with special reference to urine routine and microscopic examination.

Overview

Brief Summary

The use of antibiotics in modern medicine has made it simpler to treat urinary tract infections, but the risks of reinfection and recurrence remain serious issues. Additionally, a significant problem is the emergence of resistance. Bhumyamalaki dravya effective in treating mutrarogas according to Raj Nighantu. According to rogaghnata of bhumyamalaki dravya it will be better choice in the management of mutrakruchhra. Bhumyamalaki contains ras- tikta kashay madhur vipak- madhur virya- sheet guna- laghu ruksha dhoshghnata- kaphpittashamak. These properties are against almost all 3 doshas which are parts of samprapti ghatak of mutrakruchhra vyadhi i.e. dosha- pittapradhan tridosha; dushya- ras dhatu (kleda); strotas- mutravaha strotas; agni- rasagni mandya. Also compounds of phyllanthin and hypophyllanthin which are chemical constituents of bhumyamalaki shows antimicrobial activity. Hence, I choose bhumyamalaki dravya to evaluate it’s effect in mutrakruchhra.

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients irrespective of their religion, profession, socioeconomic and marital status will be included in study.
  • Patients with signs and symptoms of mutrakruchhra as per samhitas will be included.

Exclusion Criteria

  • Age group below 18years and above 60years.
  • Known case of chronic kidney diseases like renal tuberculosis,acute glomerulo nephritis,renal failure, nephritic syndrome also patients with congenital abnormalities, known case of benign prostatic hyperplasia, diabetes mellitus, patients with history of systemic illnesses like endocrine disorders, immunodeficiency disorders like AIDS.
  • Patients of sannipatik,purishaj,ashmarij,shukraj,abhighataj,sharkaraj mutrakruchhra.
  • Women which are in Antenatal care(ANC) and Postnatal care(PNC) state.

Outcomes

Primary Outcomes

To study the effect of bhumyamalaki kwath in mutrakruchhra with special reference to urine routine and microscopic examination.

Time Frame: 15 days

Secondary Outcomes

  • 1.To study the ayurvedic aspect of mutrakruchhra vyadhi in detail.(2.To study the urinary tract infection as per modern science.)

Investigators

Sponsor
Dr Jyotsna Raghunath Payamal
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr Jyotsna Raghunath Payamal

LRP Ayurvedic Medical College And Hospital Islampur

Study Sites (1)

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