Correlation of Bispectral Index with Depth of Sedation: A Comparison Between Dexmedetomidine and Propofol in Patients Undergoing Abdominal Surgery Under General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
This is a prospective randomized comparative clinical study conducted in adult patients undergoing elective abdominal surgery under general anesthesia. The study aims to evaluate the correlation between bispectral index values and depth of sedation using dexmedetomidine and propofol.
A total of sixty patients belonging to ASA physical status one and two will be randomly allocated into two groups. Group D will receive dexmedetomidine infusion and Group P will receive propofol infusion for intraoperative sedation. Standard anesthesia monitoring along with bispectral index monitoring will be used in all patients.
Depth of sedation will be assessed using bispectral index values and Ramsay sedation scale at predefined intraoperative time points. Hemodynamic parameters recovery characteristics and adverse events will also be recorded and compared between the two groups.
The study aims to determine the correlation between bispectral index and clinical depth of sedation and to compare the efficacy and safety of dexmedetomidine and propofol during abdominal surgery under general anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged eighteen to sixty five years of either gender belonging to ASA physical status one or two scheduled for elective abdominal surgery under general anesthesia and willing to provide written informed consent.
排除标准
- •Patients with neurological disorders affecting electroencephalogram, chronic use of sedatives or opioids, severe cardiac hepatic or renal disease, known allergy to study drugs, pregnant or lactating women and patients unwilling to participate.
研究者
Saptagiri Mypati
Vinayaka Missions Kirupananda Variyar Medical College & Hospital