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FallriskPD: fall risk evaluation in Parkinson’s disease using intelligent gait analysis. - FallRiskPD

niversitätsklinikum Erlangen, Molekular-Neurologische Abteilung0 个研究点目标入组 51 人开始时间: 2018年9月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
51

研究概览

简要总结

This study present a data set containing real-world gait and unsupervised 4x10-Meter-Walking-Tests of 40 PD patients, continuously recorded with foot-worn inertial sensors over a period of two weeks. In this prospective study, falls were self-reported during a three-month follow-up phase, serving as ground truth for fall risk prediction. The purpose of this study was to compare different data aggregation approaches and machine learning models for the prospective prediction of fall risk using gait parameters derived either from continuous real-world recordings or from unsupervised gait tests. The highest balanced accuracy of 74.0% (sensitivity: 60.0%, specificity: 88.0%) was achieved with a Random Forest Classifier applied to the real-world gait data when aggregating all walking bouts and days of each participant. Our findings suggest that fall risk can be predicted best by merging the entire two-week realworld gait data of a patient, outperforming the prediction using unsupervised gait tests (68.0% balanced accuracy) and contribute to an improved understanding of fall risk prediction.

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 one(—)
性别
All

入选标准

  • Diagnosis of a Parkinson syndrome in accordance with the guideline of the German Society of Neurology (Hoehn & Yahr stadium I-III)
  • - Ability to walk for 2 Minutes without assistance
  • - Ability to speak and read
  • - Ability to use an application running on a smart device
  • - informed consent with understanding of the study procedures

排除标准

  • - Aphasia and Alexia
  • - Impaired vision which makes reading unfeasible
  • - Regular use of gait aids
  • - Decompensated cardiopulmonary restrictions
  • - Maximal walking distance < 100 meter
  • - Inability to understand the informed consent and the study procedures
  • - Distinct musculoskeletal disorder, which highly restricts movement and gait abilities

研究者

发起方
niversitätsklinikum Erlangen, Molekular-Neurologische Abteilung

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FallriskPD: fall risk evaluation in Parkinson’s... | 临床试验