Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study

Completed

• Conditions: Maculopapular Exanthem; Stevens-Johnson Syndrome; Drug-Induced Rash; Drug Reaction With Eosinophilia and Systemic Symptom; Vitamin D Deficiency

• Registration Number: NCT06263140
• Lead Sponsor: Chulalongkorn University

Brief Summary

Serum vitamin D levels in drug-induced non-immediate reactions

Detailed Description

The study of serum vitamin D levels in patients presented with drug-induced non-immediate cutaneous adverse reactions compared to those in drug-tolerant control subjects

Study Timeline

• Study Start: 2021-05-30
• Primary Completion: 2022-01-15
• Status Verified: 2022-02
• Study Completion: 2022-02-01
• Study First Submitted: 2022-02-09
• Study First Submitted QC: 2024-02-14
• Last Update Submitted: 2024-02-14
• Study First Posted: 2024-02-16
• Last Update Posted: 2024-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• Diagnosed with SJS/TEN, DRESS, AGEP, MPE, or FDE as mentioned above

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Exclusion Criteria

• Reactions from drugs with known strong genetic predispositions (allopurinol, carbamazepine, abacavir)
• Receiving vitamin D supplement

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum vitamin D levels	At baseline	Serum vitamin D levels at baseline

Trial Locations

Locations (1)

Faculty of Medicine, Chulalongkorn University; 🇹🇭 Bangkok, Thailand