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Clinical Trials/NCT04301687
NCT04301687
Not yet recruiting
Not Applicable

The Analgesic Efficacy of the Ultrasound-Guided Femoral Articular Branch Block for Ambulatory Hip Arthroplasty: A Randomized-Controlled Trial Secondary IDs:

Women's College Hospital0 sites95 target enrollmentDecember 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Hip Arthroplasty
Sponsor
Women's College Hospital
Enrollment
95
Primary Endpoint
Analgesic Consumption
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

Hip arthroplasty surgery can be associated with significant pain. A regional anesthesia technique, the femoral articular branch block (FAB), has recently been proposed to collectively block terminal femoral and accessory obturator nerve branches to the hip joint with a single injection, theoretically blocking most of the innervation relevant to hip arthroscopy while sparing the main femoral nerve branches to the quadriceps muscles. The investigators aim to demonstrate the analgesic benefits of FAB. The investigators hypothesize that FAB will reduce opioid consumption and improve postoperative quality of recovery in patients having hip arthroplasty. This is a randomized, controlled, double-blind study and half the patients will be randomized to receive the femoral articular branch block and the other half of patients will be randomized to receive a placebo block. A comparison of pain will be made between both groups.

Detailed Description

Hip arthroplasty procedure is frequently associated with severe post-operative pain despite the practice of injecting the hip joint with local anesthetics at the end of the procedure and the use of intraoperative opioids. These patients usually receive a spinal anesthetic as well. The ideal analgesic technique that provides adequate pain relief following this procedure has not been established yet. The femoral articular branch block (FAB) has recently been proposed to collectively block the terminal femoral and accessory obturator nerve branches to the hip joint with a single injection, theoretically blocking most of the innervation relevant to hip arthroscopy while sparing the main femoral nerve branches to the quadriceps muscle. The investigators aim to demonstrate the analgesic benefits of FAB.

Registry
clinicaltrials.gov
Start Date
December 2025
End Date
December 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • ASA I-III patients
  • Ages 18-60yrs
  • BMI ≤ 35 kg/m2

Exclusion Criteria

  • Preexisting neurological deficits or peripheral neuropathy in the distribution of femoral, obturator, or lateral cutaneous nerves
  • Local infection
  • Contra-indication to regional anesthesia e.g. bleeding diathesis, coagulopathy
  • Chronic pain disorders
  • History of use of over 30mg oxycodone or equivalent per day
  • Contraindication to a component of multi-modal analgesia
  • Allergy to local anesthetics
  • History of significant psychiatric conditions that may affect patient assessment
  • Pregnancy
  • Inability to provide informed consent

Outcomes

Primary Outcomes

Analgesic Consumption

Time Frame: 24 hours postoperatively

Postoperative cumulative oral morphine equivalent consumption during the first 24 hours will be the first primary outcome

Quality of Life scores

Time Frame: 24 hours postoperatively

Quality of Recovery (QR15) scores at 24 hours will be the second primary outcome.

Secondary Outcomes

  • Analgesic Consumption(Up to 48 hours following surgery)
  • Pain Assessment (VAS)(Up to 48 hours post-operatively)
  • Block Success(4 hours after nerve block has been administered)
  • Incidence of block-related complications(Up until one month following nerve block)
  • Patient Satisfaction with Analgesic Technique(One month after surgery)
  • Demographic Data(Day 1 - first 24 hours)
  • Incidence of opioid-related side effects(Up until one month following nerve block)

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