A phase II study of Bevacizumab and Docetaxel for elderly patients advanced Non-Small Cell Lung Cancer
- Conditions
- on-squamous non-small cell lung cancer
- Registration Number
- JPRN-UMIN000006322
- Lead Sponsor
- niversity hospital, Hirosaki University School of Medicine Cardiology,respiratory medicine and nephrology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Not provided
1)Subjects with interstitial pneumonia or pulmonary fibrosis. 2)Uncontrolled systematic disease 3)Uncontrolled active infection 4)No other active malignancies 5)Concurrent use of steroid therapy 6)Subjects with brain metastases 7)Uncontrolled pleural effusion and ascites 8)have had or require continuous oral administration of hemostat/have had or require injectable administration of hemostat 9)Pregnant patients 10)Have a bleeding diathesis 11)Tumor invasion to major vessels 12)Cavity in tumor 13)History of uncontrolled gastroduodenal ulcer 14)Uncontrolled hypertension 15)Symptomatic heart failure,unstable angina, uncontrolled arrhythmia, myocardial infarction within 1 year 16)Symptomatic cerebrovasucular disease 17)Any other reason that,in the opinion of the investugator precludes the subject from participating in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method RR: response rate
- Secondary Outcome Measures
Name Time Method PFS: progression free survival OS: overall survival safety