Morbidity in elderly travelers during a short-term stay abroad, a prospective cohort study
- Conditions
- Infecties, verergering onderliggend medisch lijdenexacerbation of age-related diseases during travel
- Registration Number
- NL-OMON43674
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 477
- 60 years and older;
- Planned travel to the (sub)tropics. (Sub)tropical areas are defined as countries where hepatitis A is endemic and for which vaccination is recommended according to the LCR.
-Travel duration of five weeks (35 days) or less.
- Ability to complete the questionnaires and diary.
- Ability to speak and read Dutch fluently.
- Ability to sign the informed consent form.
- 59 years or younger.
- Travel to a destination for which no hepatitis A vaccination is recommended according to the LCR.
- Inability to complete questionnaires and diary.
- Travel duration longer than 5 weeks (>35 days)
- Visit to travel clinic is less than two weeks before departure.
- Inability to speak or read Dutch.
- Inability to complete questionnaire and diary.
- Incapacitated travelers.
- Absence of written informed consent.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main endpoints of the primary objective are the occurrence, duration in<br /><br>days and morbidity of an acquired illness during travel and four weeks after<br /><br>return. The focus will be on different type of health complaints:<br /><br>- Fever<br /><br>- Gastrointestinal<br /><br>- Respiratory<br /><br>- Dermatological<br /><br>- Cardiovascular<br /><br>- Genitourinary tract<br /><br><br /><br>Other endpoints of the objective are:<br /><br>- Hand grip strength in kilograms before travel (vitality).<br /><br>- Patient-reported health before, during and after travel (SF-36 and Charlson<br /><br>Comorbidity Index).<br /><br>- Independence in activities of daily living (Katz-ADL).<br /><br>- Cognitive functioning before travel (6CIT).</p><br>
- Secondary Outcome Measures
Name Time Method