A surveillance study investigating whole body magnetic resonance imaging and other diagnostic procedures in people at high risk of cancer

Not Applicable

Recruiting

• Conditions: Cancer; Cancer - Any cancer

• Registration Number: ACTRN12613000987763
• Lead Sponsor: Australasian Sarcoma Study Group

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-09-04
• Last Update Posted: 9 August 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Known cancer risk gene pathogenic mutation carrier or family member at 50% risk of carrying a mutation
ECOG performance status 0 or 1
No active cancer diagnosis. This is defined as the primary tumour having been treated
with no clinical or symptomatic evidence of metastatic disease
Expected lifespan greater than 3 years

Exclusion Criteria

Inability to provide informed consent
Serious co-morbid illness
Active cancer diagnosis
Inability to undergo study procedures
Inability to understand an English language consent form
Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presence of at least one investigable lesion in a patient at baseline will be used to calculate the prevalence of investigable lesions by whole body MRI scan. [Baseline];The presence of at least one new investigable lesion in a patient after 1, 2 and 3 years will be used to calculate the 1, 2 and 3 year incidences respectively by whole body MRI scan.[1, 2 and 3 years]