Surgery alone versus Surgery with Extensive intraperitoneal lavage for locally advanced gastric cancer -A comparison of short term postoperative outcomes
Phase 2
- Conditions
- Health Condition 1: C169- Malignant neoplasm of stomach, unspecified
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All the patients who are more than 18 years of age and preoperatively - cT3 or 4 N0-3 M0 (according to AJCC, 8th edition) undergoing open total or subto-tal gastrectomy for locally advanced gastric adenocarcinoma, with ECOG performance status 0 or 1
Exclusion Criteria
1.Received neoadjuvant therapy.
2.Patients with co-existing uncontrolled comorbidities.
3.Recurrent carcinoma of stomach.
4.Presence of other coexisting malignancy.
5.Other types of gastric cancer such as lym-phoma, GIST, carcinoid tumor.
6.Emergency gastrectomy for bleeding or per-forated gastric cancer.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of extensive intraperitoneal lavage with surgery & surgery alone on the incidence of surgical site infection in patients undergoing D2 gastrectomy for locally advanced carcinoma of stomach.Timepoint: Upto 30 days from the day of surgery.
- Secondary Outcome Measures
Name Time Method 1.Postoperative pain (using Visual Analogue Scale) <br/ ><br>2.Gastrointestinal (GI) complications such as: <br/ ><br>a.Bowel obstruction/ileus. <br/ ><br>b.Anastomotic leak. <br/ ><br>3.Non-GI complications such as: <br/ ><br>a.Pulmonary complications (atelectasis, pleural effusion, Pulmonary thromboembolism). <br/ ><br>b.Deep vein thrombosis (DVT). <br/ ><br>c.Pneumonia. <br/ ><br>4.Reoperation. <br/ ><br>5.Readmission rates within 30 days <br/ ><br>6.Mortality within 30 days of surgery <br/ ><br>Timepoint: Upto 30 days from the day of surgery.