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Epidemiological and Clinical Characteristics of Hospitalized Patients Under 5 Years Old With RSV Infection in Central China, Wuhan

Conditions
RSV Infection
Interventions
Other: Observation
Registration Number
NCT05767294
Lead Sponsor
Tongji Hospital
Brief Summary

The study will be a multicenter, hospital-based retrospective study. We plan to collect the clinical and laboratory data among all hospitalized ARTI cases in three hospitals in Wuhan from June 1, 2020 to May 31, 2023 and then analyze the epidemiological and clinical characteristics of RSV infection, clarify the gene types of epidemics under 5 years old children after the outbreak in Wuhan, China.

Detailed Description

Not available

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
10000
Inclusion Criteria

①Admission age <5 years old

②Clinical diagnosis of acute respiratory tract infections

Exclusion Criteria

Hospital acquired ARTI

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
1-3 months oldObservation-
NeonatalObservation-
3-6 months oldObservation-
6 months-1 year oldObservation-
1-2 years oldObservation-
2-5 years oldObservation-
Primary Outcome Measures
NameTimeMethod
genderat admission

female/male

number of patients with feverat admission

number of patients with fever

number of patients with underlying diseaseat admission

underlying disease include immune deficiency, CHD, BPD, BO, bronchiectasis and asthma and so on

number of patients with treatment of immunoglobulinthrough study completion, an average of 1 year

number of patients with treatment of immunoglobulin

number of patients with treatment of glucocorticoidsthrough study completion, an average of 1 year

number of patients with treatment of glucocorticoids

proportion of different virus genotypethrough study completion, an average of 1 year

virus genotype include A, B and C

number of patients infected with virusthrough study completion, an average of 1 year

number of patients infected with virus

F protein gene sequencethrough study completion, an average of 1 year

F protein gene sequence

number of patients with shortness of wheezeat admission

number of patients with shortness of wheeze

number of patients with shortness of stridorat admission

number of patients with shortness of stridor

ageat admission

age

number of patients with coughat admission

number of patients with cough

number of patients with shortness of vomitat admission

number of patients with shortness of vomit

number of patients with shortness of raleat admission

number of patients with shortness of rale

number of patients with treatment of ventilationthrough study completion, an average of 1 year

number of patients with treatment of ventilation

direct medical costthrough study completion, an average of 1 year

direct medical cost

number of patients with shortness of breathat admission

number of patients with shortness of breath

number of patients with treatment of antibioticthrough study completion, an average of 1 year

number of patients with treatment of antibiotic

Imaging examination resultsthrough study completion, an average of 1 year

X-Ray/CT

length of hospital stay length of stay length of staythrough study completion, an average of 1 year

length of hospital stay

number of patients with treatment of oxygen inhalationthrough study completion, an average of 1 year

number of patients with treatment of oxygen inhalation

number of patients infected with bacteriathrough study completion, an average of 1 year

number of patients infected with bacteria

number of patients infected with fungusthrough study completion, an average of 1 year

number of patients infected with fungus

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

department of pediatrics, Tongji hospital, Tongji medical college, Huazhong University of Science and Technology

🇨🇳

Wuhan, Hubei, China

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