Analgesic Efficacy of Meloxicam Versus Ibuprofen for Pain Control After Third Molar Extraction in Adult Patients: Randomized Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 68
- 主要终点
- Meloxicam effectiveness for post-surgical pain control.
研究概览
简要总结
Third molar extraction is a common dental procedure, offently related with pain and swelling. The purpose of this study is to evaluate if Meloxicam has a better effect relieving pain after the extraction than Ibuprofen, one of the most common pain relieving drugs administered after this procedure.
详细描述
Summary: Third molar extractions are one of the most common procedures in dental practice. However, pain and swelling as postoperative sequelae are inevitable. Depending on the level of pain, which can range from moderate to severe, this symptomatology can be accompanied with pharmacological treatment, thus generating a less traumatic recovery for the patient. It is currently known that non-steroidal anti-inflammatory drugs (NSAIDs) have proven to be effective for the treatment of mild and moderate postoperative pain. Due to the wide variety of NSAIDs, it is important to know how to choose the most effective option when indicating one therapeutic option over another.
Objective
To evaluate the postoperative analgesic effectiveness of meloxicam (7.5 mg) compared to ibuprofen (400 mg) in patients undergoing third molar(s) extraction.
Design: Randomized controlled clinical trial, double-masked, designed according to CONSORT guideline requirements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 59 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Maxillary or mandibular third molar with semi or fully erupted crown.
排除标准
- •Patients with Systemic pathologies. Presence of third molar localized infection. Completely included third molar crown. Periodontal compromise. Pregnant or breastfeeding women. Patients with hypersensitivity to NSAIDs. Patients with a history of drug abuse. Patients who had taken any drug in the previous 24 hours. Intervention (exodontia) time longer than 45 minutes.
研究组 & 干预措施
Group A control. Ibuprofen
Ibuprofen 400mg tablets, 1 every 8 hours for 3 days will be administered for post-surgical pain.
干预措施: meloxicam 7,5mg (Drug)
Group B experimental. Meloxicam
Meloxicam 7.5mg tablets, 1 every 12 hours for 3 days will be administered for post-surgical pain.
干预措施: meloxicam 7,5mg (Drug)
结局指标
主要结局
Meloxicam effectiveness for post-surgical pain control.
时间窗: 3 days
A visual analogue scale ranging from 0 points (no pain) to 10 points (intolerable pain) will be used to measure post-exodontic pain, and values will be recorded on a questionnaire.
次要结局
未报告次要终点