TO STUDY THE EFFICACY OF PROBIOTIC SUPPLEMENTATION ON OBESITY LIPID PROFILES AND INSULIN RESISTANCE IN WOMEN WITH PCOS
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- Probiotic supplementation may improve lipid metabolism disturbances weight BMI insulin HOMA IR and hormonal profiles associated with PCOS indicating its potential role to protect fertility
研究概览
简要总结
The following study will include women diagnosed with PCOS as per modified Rotterdam criteria in the age group of 18-40 yrs visiting the OBG OPD in SHRI BM Patil medical college and R C with BMI > 25
after considering inclusion and exclusion criteria patients with enrolled
pre interventional investigations will the collected
anthropometric parameters such as BMI
height
weight
waist circumference
hip circumference
lab parameters such as lipid profile, fasting blood glucose, fasting insulin level
Probiotics will be prescribed for 12 weeks
after 12 weeks post interventional parameters will be noted
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Day(s) 至 40.00 Day(s)（—）
- 性别
- Female
入选标准
- •women diagnosed with PCOS with BMI more than 25.
排除标准
- •Presently on probiotic supplements Endocrine disorders, such as diabetes, thyroid, and poor glucose tolerance.
- •K/c/o GI disorders (irritable bowel syndrome, celiac disease, and food allergies) K/c/o autoimmune disease.
- •Probiotic capsules allergy.
结局指标
主要结局
Probiotic supplementation may improve lipid metabolism disturbances weight BMI insulin HOMA IR and hormonal profiles associated with PCOS indicating its potential role to protect fertility
时间窗: Probiotic supplementation for 12 weeks may improve lipid metabolism disturbances weight BMI insulin HOMA IR and hormonal profiles associated with PCOS indicating its potential role to protect fertility
次要结局
- probiotic supplementation to improve hormonal parameters(12 weeks)
研究者
DR RUTUJA BODAKE
SHRI B M PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTER