Assessment of Capnography in Monitoring Patients during Deep Sedation with Propofol

Completed

Conditions: iatrogeen veroorzaakte hypoventilatie door sedatie
alveolar hypoventilation
oxygen debt
10000211

Registration Number: NL-OMON35334

Lead Sponsor: Centra voor Anticonceptie, Seksualiteit en Abortus CASA

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 440

Inclusion Criteria

Age 18 years or older
Abortion procedures performed until 22 weeks of gestational age
American Society of Anaesthesiologists (ASA) classes I to II (normal healthy patients or patients with a mild systemic disease)
Ability to give written informed consent.

Exclusion Criteria

Inability to provide written informed consent
History of allergic reactions to propofol, soybeans or egg proteins
American Society of Anaesthesiologists (ASA) classes III to V (patients with a severe systemic disease, with or without constant threat to life, or moribund patients)
Sleep apnea syndrome
Patients with known seizure disorders

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome for both groups is the number of patients with oxygen<br /><br>saturations to <=90% (minor hypoxemia), as measured by continuous pulse<br /><br>oximetry. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study outcomes are the number of patients with saturations to <=80%<br /><br>(major hypoxemia), dose of administered propofol, problems during the abortion<br /><br>procedure, airway interventions, early termination of the procedure due to<br /><br>respiratory problems, episodes of bradycardia, and administration of atropine.</p><br>