An open randomised trial of patient controlled analgesia (PCA) versus routine care in the Emergency Department

Plymouth Hospitals NHS Trust (UK)0 个研究点目标入组 400 人开始时间: 2011年7月4日最近更新: 2016年10月17日

适应症

试验速览

暂无简介。

•1. Adult patients aged between 18 and 75 years of age inclusive
•2. Traumatic injuries or non-traumatic abdominal pain
•3. In severe pain on arrival in the Emergency Department
•4. Admission to hospital is intended at the time of enrolment
•5. Provision of informed consent to participate.; Target Gender: Male & Female; Upper Age Limit 75 years ; Lower Age Limit 18 years

•1. Patients over 75 years
•2. Patients with a reduced conscious level
•3. Inability to operate a PCA device
•4. Patients who cannot understand the study information (e.g. due to pre-existing dementia, learning difficulties, or intoxication)
•5. Patients with chronic pain
•6. Patients who are opioid tolerant
•7. Patients with active opioid addiction
•8. Patients with a history of renal failure
•9. Allergy or other contraindication to morphine
•10. Hypotension (systolic blood pressure <90mmHg)
•11. Patients in police custody, or prisoners
•12. Inability to gain intarvenous (IV) access
•13. Patients who are likely to be definitively treated in the ED and discharged
•14. Patients who are pregnant or breastfeeding
•15. Open fractures (excluded because this group of patients will undergo surgery within six hours of injury according to national standards)
•16. Patients on other predetermined analgesia pathway (e.g. regional anaesthesia)
•17. Previous participation in this study
•18. Current participation in another Clinical Trial of an Investigational Medicinal Product (CTIMP)

发起方

Plymouth Hospitals NHS Trust (UK)