ISRCTN84763265CompletedNot Applicable
A prospective cohort study examining the effect of 12 weeks of intensive endurance exercise on insulin sensitivity and muscle insulin signalling in overweight women with or without polycystic ovary syndrome (PCOS)
Southern Health (Australia)0 sites30 target enrollmentStarted: January 23, 2009Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 30
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- Female
Inclusion Criteria
- •1. Overweight women (body mass index [BMI] greater than 27 kg/m^2)
- •2. Aged 18 - 40 years with PCOS and without
- •3. Diagnosed from a history of perimenarchal onset of irregular cycles (less than 21 days or greater than 35 days)
- •4. Clinical manifestations of hyperandrogenism (hirsutism, acne) or biochemical hyperandrogenism with elevation of at least one circulating ovarian androgen (1990 National Institute of Health [NIH] criteria)
Exclusion Criteria
- •1. BMI less than 27 kg/m^2
- •2. Other concurrent medical conditions
- •3. Ongoing use of the oral contraceptive pill (OCP)
- •4. Pregnancy or desire for pregnancy
- •5. Secondary causes of amenorrhoea and hyperandrogenism
Investigators
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