NL-OMON48390已完成不适用
Molecular phenotyping of Mast Cells in Indolent Systemic Mastocytosis using Single Cell RNA-sequencing - MC-ISM
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- A clinical suspicion of ISM, based on a constellation of clinical complaints,
- •including drowsiness, gastro-intestinal complaints, myalgia and fatigue, or
- •manifestations such as urticaria pigmentosa, osteoporosis or anaphylaxis.
- •- Eligible for a bone marrow biopsy
- •- Legally capacitated adults
- •-The second eligible patient group concerns patient enrolled in the
- •avapritinib study (research register number 201800849, METc 2018.635). These
- •patients with a confirmed diagnosis of ISM willl undergo a bone marrow biopsy
- •as part of the study protocol of the avapritinib study. Therefore, also in this
- •patient population no additional invasive procedures are required, hence the
- •additional burden of the current study remains restricted to the withdrawal of
- •the additional sample.
排除标准
- •Lidocaine hypersensitivity.
研究者
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