Mild Traumatic Brain Injury and the Risk for Traumatic Intracranial Hemorrhage in Patients on Oral Antithrombotic Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,044
- 试验地点
- 1
- 主要终点
- traumatic Intracranial hemorrhage
研究概览
简要总结
Management of traumatic brain injuries causes significant efforts on emergency departments (ED) and overall health care. Patients on antithrombotic treatment with even minor trauma to the head, although without significant clinical findings, represent special challenges because the risk of traumatic intracranial hemorrhage (tICH) with these agents. The aim of this study was to compare the prevalence of tICH in patients on various pre-injury antithrombotic treatment exposed to minor Traumatic Brain injuries (mTBI) in Sundsvall with untreated patients. Secondary aim was to explore different risk factors for tICH.
Data from medical records and radiology registry with mTBI in Sundsvall hospital between 2018-2020 in Sundsvall identified 2044 patients. Demographic data, pre-injury medications with antithrombotic treatment, state of consciousness at admission and the results of CT-scans of brain was investigated.
详细描述
Inclussion criteria:
- low energy traumas to the head,
- pre-injury antithrombotic treatment,
- > 18 years,
- reaction level scale (RLS) < 3.
Since data collection started at the hospital's radiology registry, we could easily retrieve all patients with low energy traumas to the head who underwent CT scans, were we also included patients without any pre-injury treatment for comparison.
Exclusion criteria:
- high energy trauma,
- spontaneous hemorrhage,
- concealed journals.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 接受健康志愿者
- 否
入选标准
- •Patients that fulfilled following criteria were included (1) low energy traumas to the head, (2) pre-injury antithrombotic treatment, (3) > 18 years, (4) reaction level scale (RLS) <
- •Since data collection started at the hospital's radiology registry, we could easily retrieve all patients with low energy traumas to the head who underwent CT scans, were we also included patients without any pre-injury treatment for comparison.
排除标准
- •Exclusion criteria were (1) high energy trauma, (2) spontaneous hemorrhage, (3) concealed journals.
结局指标
主要结局
traumatic Intracranial hemorrhage
时间窗: Jan 1st 2018 till May 30th 2020
In this retrospective study, all CT-scan referrals from surgical branch of the emergency department and acute surgical department, suspecting traumatic brain hemorrhage, were included. The studied period was between Jan 1st 2018 till May 30th 2020. Patients with an traumatic Intracranial hemorrhage were subcategorized into subdural, subarachnoid, epidural, and other.
次要结局
未报告次要终点