Choline uptake study - CUP-Study

Apparently healthy men and women

Age between 30 and 70 years

Body mass index (BMI) between 18.5 and 24.9 kg/m2

Having veins suitable for blood sampling via a catheter (judged by study nurse/ medical doctor)

Any metabolic, gastrointestinal, inflammatory or chronic disease (such as diabetes, anaemia, hepatitis, cardiovascular disease)

History of gastro-intestinal surgery or having (serious) gastro-intestinal complaints

History of liver dysfunction (cirrhosis, hepatitis) or liver surgery

Kidney dysfunction (self-reported)

Use of medication that may influence the study results, such as laxatives, stomach protectors and drugs that can affect intestinal motility

Use of fishoil or choline supplements

Reported slimming, medically prescribed or vegan diet

Current smokers

Alcohol intake *4 glasses of alcoholic beverages per day

Pregnant, lactating or wishing to become pregnant in the period of the study (self-reported)

Abuse of illicit drugs

Food allergies for products that we use in the study

Participation in another clinical trial at the same time

Being an employee of the department Consumer Science & Health group of Wageningen Food & Biobased Research