The Effect of the COVID-19 Pandemic on Frailty in Liver Transplant Candidates
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 208
- 试验地点
- 2
- 主要终点
- To determine the impact of the COVID-19 pandemic on the incidence of sarcopenia
研究概览
简要总结
Frailty is associated with higher rates of morbidity, mortality, and failure to rescue after major surgical procedures. Sarcopenia is degenerative loss of skeletal muscle mass and strength. It is a key component of physical frailty and is associated with poorer post-surgical outcomes due to decreased patient strength and vitality.
详细描述
This study seeks to examine whether the (COVID-19) pandemic, an ongoing global health crisis that was declared a national emergency by the US Federal Government on March 13, 2020, has exacerbated both frailty and sarcopenia in a population of liver transplant candidates.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 years and older Underwent pre-transplant frailty assessment (PFA) at MDMC
排除标准
- •Not a patient at Liver Institute at Methodist Dallas
结局指标
主要结局
To determine the impact of the COVID-19 pandemic on the incidence of sarcopenia
时间窗: 2 years
To determine the impact of the COVID-19 pandemic on the incidence of sarcopenia and frailty in patients undergoing liver transplant evaluation at Methodist Dallas Medical Center
To determine the impact of the COVID-19 pandemic on the prevalence of sarcopenia
时间窗: 2 years
To determine the impact of the COVID-19 pandemic on the prevalence of sarcopenia and frailty in patients undergoing liver transplant evaluation at Methodist Dallas Medical Center
次要结局
- Changes in number of comorbidities between pre- and during/post-pandemic periods(1 year)
- Changes in severity of comorbidities between pre- and during/post-pandemic periods(1 year)
- Changes in type of comorbidities between pre- and during/post-pandemic periods(1 year)