The Effect of the COVID-19 Pandemic on Frailty in Liver Transplant Candidates
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Frailty
- Sponsor
- Methodist Health System
- Enrollment
- 208
- Locations
- 1
- Primary Endpoint
- To determine the impact of the COVID-19 pandemic on the incidence of sarcopenia
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Frailty is associated with higher rates of morbidity, mortality, and failure to rescue after major surgical procedures [1]. Sarcopenia is degenerative loss of skeletal muscle mass and strength. It is a key component of physical frailty and is associated with poorer post-surgical outcomes due to decreased patient strength and vitality.
Detailed Description
This study seeks to examine whether the SARS-CoV-2 (COVID-19) pandemic, an ongoing global health crisis that was declared a national emergency by the US Federal Government on March 13, 2020, has exacerbated both frailty and sarcopenia in a population of liver transplant candidates.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 18 years and older Underwent pre-transplant frailty assessment (PFA) at MDMC
Exclusion Criteria
- •Not a patient at Liver Institute at Methodist Dallas
Outcomes
Primary Outcomes
To determine the impact of the COVID-19 pandemic on the incidence of sarcopenia
Time Frame: 2 years
To determine the impact of the COVID-19 pandemic on the incidence of sarcopenia and frailty in patients undergoing liver transplant evaluation at Methodist Dallas Medical Center
To determine the impact of the COVID-19 pandemic on the prevalence of sarcopenia
Time Frame: 2 years
To determine the impact of the COVID-19 pandemic on the prevalence of sarcopenia and frailty in patients undergoing liver transplant evaluation at Methodist Dallas Medical Center
Secondary Outcomes
- Changes in number of comorbidities between pre- and during/post-pandemic periods(1 year)
- Changes in severity of comorbidities between pre- and during/post-pandemic periods(1 year)
- Changes in type of comorbidities between pre- and during/post-pandemic periods(1 year)