Phase 2b Study of VELCADE Alone and VELCADE Plus Irinotecan in Patients With Relapsed or Refractory Colorectal Carcinoma
- Conditions
- Colorectal Carcinoma
- Registration Number
- NCT00051987
- Lead Sponsor
- Millennium Pharmaceuticals, Inc.
- Brief Summary
The purpose of this study is to evaluate how tumors in patients with colorectal carcinoma respond to treatment with VELCADE alone versus VELCADE given with irinotecan, and also to see what effects (good and bad) it has on you and your cancer.
- Detailed Description
In this study, patients with colorectal cancer that is no longer responding to standard medical treatment with irinotecan or an irinotecan containing treatment will be randomized to treatment with VELCADE alone or to treatment with VELCADE in combination with irinotecan.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 175
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (22)
USC/Norris Comprehensive Cancer Center
🇺🇸Los Angeles, California, United States
California Cancer Center
🇺🇸Greenbrae, California, United States
St. Lukes Rossevelt Hospital
🇺🇸New York, New York, United States
West Michigan Regional Cancer and Blood Center
🇺🇸Ludington, Michigan, United States
Oregon Health Sciences
🇺🇸Portland, Oregon, United States
Alta Bates Comprehensive Cancer Center
🇺🇸Berkley, California, United States
H. Lee Moffit Cancer Center
🇺🇸Tampa, Florida, United States
New York University
🇺🇸New York, New York, United States
Memphis Cancer Center, PC
🇺🇸Memphis, Tennessee, United States
UNC School of Medicine
🇺🇸Chapel Hill, North Carolina, United States
University of Texas Health Sciences Center at San Antonio
🇺🇸San Antonio, Texas, United States
Cooper Green Hospital / Jefferson Clinic P.C.
🇺🇸Birmingham, Alabama, United States
City of Hope Medical Group
🇺🇸Pasadena, California, United States
Kentuckiana Cancer Institute, PLLC
🇺🇸Louisville, Kentucky, United States
Bond Clinic Inc.
🇺🇸Rolla, Missouri, United States
Rush Cancer Institute
🇺🇸Chicago, Illinois, United States
Ohio State University Medical Center
🇺🇸Columbus, Ohio, United States
Norris Cotton Cancer Center
🇺🇸Lebanon, New Hampshire, United States
The Cancer Institute of New Jersey
🇺🇸New Brunswick, New Jersey, United States
Arkansas Cancer Center
🇺🇸Pine Bluff, Arkansas, United States
Arizona Cancer Center
🇺🇸Tucson, Arizona, United States
Nevada Cancer Center
🇺🇸Las Vegas, Nevada, United States