The effect of high-intensity interval training (HIIT) and vitamin D supplementation on older me
Not Applicable
Not yet recruiting
- Conditions
- Sarcopenia.Muscle wasting and atrophy, not elsewhere classifiedM62.5
- Registration Number
- IRCT20190917044797N2
- Lead Sponsor
- The University of tabriz
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Age range 60 to 75 years
inactive (less than 90 minutes of regular exercise per week)
Do not use drugs and anabolic supplements, blood pressure, anti-inflammatory and antioxidants
Exclusion Criteria
The elderly are injured
Metabolic and cardiovascular diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum levels of vitamin D. Timepoint: 48 hours before and after 8 weeks of exercise training. Method of measurement: Using the ELISA method.;Serum levels of Insulin-like hormone 1. Timepoint: 48 hours before and after 8 weeks of exercise training. Method of measurement: Using the ELISA method.;Serum levels of myostatin hormone. Timepoint: 48 hours before and after 8 weeks of exercise training. Method of measurement: Using the ELISA method.;MiRNA-1. Timepoint: 48 hours before and after 8 weeks of exercise training. Method of measurement: Real Time PCR technique.;MiRNA-133a. Timepoint: 48 hours before and after 8 weeks of exercise training. Method of measurement: Real Time PCR technique.;MiRNA-206. Timepoint: 48 hours before and after 8 weeks of exercise training. Method of measurement: Real Time PCR technique.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the effect of HIIT and vitamin D on sarcopenia in older men?
How does HIIT combined with vitamin D supplementation compare to standard resistance training for muscle atrophy in M62.5 patients?
Which biomarkers are associated with response to high-intensity interval training in sarcopenic older men?
What are the potential adverse events of 8-week HIIT regimens in elderly populations with muscle atrophy?
Are there synergistic effects of vitamin D with other anabolic agents like testosterone or selective androgen receptor modulators in sarcopenia management?