MedPath

Improving Informed Decision Making for Cancer Clinical Trial Participation

Not Applicable
Active, not recruiting
Conditions
Educational Problems
Interventions
Other: Clinical Trial Educational Video
Other: Clinical Trial Fact Sheet
Other: Low literacy booklet
Other: Navigator
Registration Number
NCT03820687
Lead Sponsor
The University of Texas Health Science Center at San Antonio
Brief Summary

The goal of this study is to develop and pilot test a multi-communication approach to improve informed decision-making about cancer Clinical Trials (CTs) participation by increasing awareness of CTs and Mays Cancer Center (MCC) services (treatment care capacities, reputation and resources), positive attitudes towards CTs, self-efficacy and intentions to consider CTs as an appropriate treatment option for cancer (intention to participate) among patients attending the MCC (clinic-based setting) and the general public in selected Bexar County areas (community-based settings).

Detailed Description

The proposed two-year study involves a randomized controlled educational trial featuring a 2-group parallel cohort design with random assignment of 400 cancer patients from the MCC to the intervention or usual care control group. Intervention participants will receive 3 components: 1) a bilingual culturally relevant educational video, 2) a low-literacy booklet and 3) support from a patient navigator to empower new cancer patients to make informed decisions about cancer CT participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider CTs as an appropriate treatment option for cancer. The usual care control group will receive a general CT fact sheet.

The community setting will involve a community awareness campaign including 400 community members, with 3 components: 1) an educational session delivered via PowerPoint presentation or flip chart, 2) a low-literacy booklet, and 3) support from a community health educator to raise awareness, positive attitudes and intentions to consider CTs as an appropriate treatment option for cancer and promote the MCC services among community members in Bexar County.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
581
Inclusion Criteria
  • Newly diagnosed cancer patients (within 1 year) attending any of the clinics at the MCC
  • Patients who have not participated in a Clinical Trial before
  • English or Spanish-speaking
  • Able to provide informed consent
Exclusion Criteria
  • Younger than 18 years
  • Patients who have already had a consultation with their doctor to discuss treatment options
  • Patients who have participated in a Clinical Trial before
  • Unable to provide informed consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Intervention GroupNavigatorParticipants in the intervention group will receive 3 components: 1) a bilingual, culturally tailored clinical trial educational video, 2) a low literacy booklet, and 3) support from a patient navigator to empower cancer patients to make informed decisions about cancer clinical trial participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider clinical trials as an appropriate treatment option for cancer.
Intervention GroupClinical Trial Educational VideoParticipants in the intervention group will receive 3 components: 1) a bilingual, culturally tailored clinical trial educational video, 2) a low literacy booklet, and 3) support from a patient navigator to empower cancer patients to make informed decisions about cancer clinical trial participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider clinical trials as an appropriate treatment option for cancer.
Usual Care Control GroupClinical Trial Fact SheetParticipants in the usual care control group will receive a general clinical trial fact sheet.
Intervention GroupLow literacy bookletParticipants in the intervention group will receive 3 components: 1) a bilingual, culturally tailored clinical trial educational video, 2) a low literacy booklet, and 3) support from a patient navigator to empower cancer patients to make informed decisions about cancer clinical trial participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider clinical trials as an appropriate treatment option for cancer.
Primary Outcome Measures
NameTimeMethod
Proportion of patients who show intention to participate or to consider CTs as an appropriate treatment option for cancer.Up to 3 months after the index oncology visit

The percentage of patients who increased intentions to participate in a CT after the intervention compared with baseline.

Secondary Outcome Measures
NameTimeMethod
Proportion of patients who show increase in knowledge/awareness regarding CT participation.Up to 3 months after the index oncology visit

The percentage of patients who improved knowledge/awareness about clinical trials after the intervention compared with baseline.

Proportion of patients who show improved attitudes regarding CT participation.Up to 3 months after the index oncology visit

The percentage of patients who improve their attitudes towards clinical trial participation after the intervention compared with baseline.

Proportion of patients eligible for designated clinical trials who actually enroll in one of these trials.Up to 3 months after the index oncology visit

The percentage of patients who actually participate, or enroll in a clinical trial if they meet the eligibility criteria.

Trial Locations

Locations (1)

University of Texas Health Science Center San Antonio, MCC

🇺🇸

San Antonio, Texas, United States

© Copyright 2025. All Rights Reserved by MedPath