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Clinical Trials/NCT03820687
NCT03820687
Active, Not Recruiting
N/A

Improving Informed Decision Making for Cancer Clinical Trial Participation

The University of Texas Health Science Center at San Antonio1 site in 1 country581 target enrollmentFebruary 8, 2023

Overview

Phase
N/A
Intervention
Clinical Trial Educational Video
Conditions
Educational Problems
Sponsor
The University of Texas Health Science Center at San Antonio
Enrollment
581
Locations
1
Primary Endpoint
Proportion of patients who show intention to participate or to consider CTs as an appropriate treatment option for cancer.
Status
Active, Not Recruiting
Last Updated
last month

Overview

Brief Summary

The goal of this study is to develop and pilot test a multi-communication approach to improve informed decision-making about cancer Clinical Trials (CTs) participation by increasing awareness of CTs and Mays Cancer Center (MCC) services (treatment care capacities, reputation and resources), positive attitudes towards CTs, self-efficacy and intentions to consider CTs as an appropriate treatment option for cancer (intention to participate) among patients attending the MCC (clinic-based setting) and the general public in selected Bexar County areas (community-based settings).

Detailed Description

The proposed two-year study involves a randomized controlled educational trial featuring a 2-group parallel cohort design with random assignment of 400 cancer patients from the MCC to the intervention or usual care control group. Intervention participants will receive 3 components: 1) a bilingual culturally relevant educational video, 2) a low-literacy booklet and 3) support from a patient navigator to empower new cancer patients to make informed decisions about cancer CT participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider CTs as an appropriate treatment option for cancer. The usual care control group will receive a general CT fact sheet. The community setting will involve a community awareness campaign including 400 community members, with 3 components: 1) an educational session delivered via PowerPoint presentation or flip chart, 2) a low-literacy booklet, and 3) support from a community health educator to raise awareness, positive attitudes and intentions to consider CTs as an appropriate treatment option for cancer and promote the MCC services among community members in Bexar County.

Registry
clinicaltrials.gov
Start Date
February 8, 2023
End Date
December 31, 2026
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor
Principal Investigator

Patricia Chalela

Associate Professor

The University of Texas Health Science Center at San Antonio

Eligibility Criteria

Inclusion Criteria

  • Newly diagnosed cancer patients (within 1 year) attending any of the clinics at the MCC
  • Patients who have not participated in a Clinical Trial before
  • English or Spanish-speaking
  • Able to provide informed consent

Exclusion Criteria

  • Younger than 18 years
  • Patients who have already had a consultation with their doctor to discuss treatment options
  • Patients who have participated in a Clinical Trial before
  • Unable to provide informed consent

Arms & Interventions

Intervention Group

Participants in the intervention group will receive 3 components: 1) a bilingual, culturally tailored clinical trial educational video, 2) a low literacy booklet, and 3) support from a patient navigator to empower cancer patients to make informed decisions about cancer clinical trial participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider clinical trials as an appropriate treatment option for cancer.

Intervention: Clinical Trial Educational Video

Intervention Group

Participants in the intervention group will receive 3 components: 1) a bilingual, culturally tailored clinical trial educational video, 2) a low literacy booklet, and 3) support from a patient navigator to empower cancer patients to make informed decisions about cancer clinical trial participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider clinical trials as an appropriate treatment option for cancer.

Intervention: Low literacy booklet

Intervention Group

Participants in the intervention group will receive 3 components: 1) a bilingual, culturally tailored clinical trial educational video, 2) a low literacy booklet, and 3) support from a patient navigator to empower cancer patients to make informed decisions about cancer clinical trial participation by increasing awareness of clinical trials and MCC services, positive attitudes and intentions to consider clinical trials as an appropriate treatment option for cancer.

Intervention: Navigator

Usual Care Control Group

Participants in the usual care control group will receive a general clinical trial fact sheet.

Intervention: Clinical Trial Fact Sheet

Outcomes

Primary Outcomes

Proportion of patients who show intention to participate or to consider CTs as an appropriate treatment option for cancer.

Time Frame: Up to 3 months after the index oncology visit

The percentage of patients who increased intentions to participate in a CT after the intervention compared with baseline.

Secondary Outcomes

  • Proportion of patients who show increase in knowledge/awareness regarding CT participation.(Up to 3 months after the index oncology visit)
  • Proportion of patients who show improved attitudes regarding CT participation.(Up to 3 months after the index oncology visit)
  • Proportion of patients eligible for designated clinical trials who actually enroll in one of these trials.(Up to 3 months after the index oncology visit)

Study Sites (1)

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