A trial of targeted repetitive Transcranial Magnetic Stimulation (rTMS) in the treatment of auditory hallucinations in schizophrenia

Not Applicable

Withdrawn

• Conditions: Auditory hallucinations in schizophrenia/schizoaffective disorder; Mental Health - Schizophrenia

• Registration Number: ACTRN12614000121662
• Lead Sponsor: Professor Paul Fitzgerald

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-31
• Last Update Posted: 2 November 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

Have a DSM-IV diagnosis of schizophrenia or schizoaffective disorder;

Are aged 18-75;

Experience auditory hallucinations that rate a minimum of 4 (moderate) on the PANSS auditory hallucinations item and are present at least on a daily basis;

Have failed to respond to a minimum of 2 adequate trials of antipsychotic medication;

Have demonstrated capacity to give informed consent.

Exclusion Criteria

Have a history of epilepsy or baseline EEG abnormalities;

Have a significant or unstable neurological disorder or a cardiac pacemaker;

Have had a previous brain injury or neurosurgery, or have any metal clips, plates or other metal items in the head;

Are currently pregnant or lactating;

Are a professional driver;

Have a history of substance abuse or dependence in the last 6 months, as determined by the DSM-IV.

Study & Design

• Study Type: Interventional
• Study Design: Not specified