Clinical Characteristics of Asthma and COPD Overlap for Patients With Asthma and COPD in Hong Kong

Recruiting

• Conditions: Asthma; COPD

• Registration Number: NCT03272932
• Lead Sponsor: Chinese University of Hong Kong

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-9-1
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br>Subjects must fulfil all of the following criteria:<br><br> - All patients with confirmed diagnosis of COPD (post-bronchodilator FEV1/FVC<0.7<br> based on the medical records) 1 or asthma (defined as those with a consistent<br> history and prior documented evidence of variable airflow obstruction, with evidence<br> of an increase in FEV1 greater than 12% or 400 mL following bronchodilator or<br> bronchial hyperresponsiveness on bronchial provocation testing, when stable) 6<br><br> - Aged >40 years old<br><br> - Signed written informed consent to participate in the study<br><br>Exclusion Criteria:<br><br> - Patients currently with acute exacerbation of COPD by GOLD definition (any worsening<br> of a patient's respiratory symptoms that is beyond normal day-to-day variations and<br> requires a change in medication) 1 or acute exacerbation of asthma by GINA<br> guideline. 6<br><br> - Patients with respiratory diseases that can show similar symptoms to chronic airway<br> diseases such as bronchiectasis, tuberculosis (TB)-destroyed lung parenchyma,<br> endobronchial TB, and lung cancer, or those who have history of these diseases based<br> on physician's judgment<br><br> - Patients currently diagnosed with pneumonia and acute bronchitis<br><br> - Patients currently randomized in other clinical studies

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage of prevalence of Asthma COPD overlap among the asthma and COPD subjects.

Secondary Outcome Measures

Name	Time	Method
Percentage of patient with treatment that is different from the guidelines recommendation;The percentages of patients on various medications (e.g. inhaled steroid, LABA, LAMA);The pecentages of patients receiving different symptoms control assessments (e.g. use of Asthma control test, use of COPD assessment test);Percentages of subjects with morbidity (e.g. congestive heart failure);Percentages of subjects with mortality;Percentages of patients with various Genetic markers