the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis

• Conditions: Varicocele
• Interventions: Procedure: High inguinal Varicocelectomy; Procedure: Subinguinal varicocelectomy

• Registration Number: NCT03281915
• Lead Sponsor: Assiut University

Brief Summary

to evalute the effect inguinal and subinguinal approach of varicoceclectomy on semen parameter for patients complaining of varicocele with normal semen parameter (pain is the main complaint)

Detailed Description

the varicocele is defined as dilated and incompetent veins within the pampiniform plexus of spermatic cord. varicocele has been described as the most common surgically correctable cause of male subinfertility.this is a disease that devolops during puberty when both endocrine and exocrine function of the testicle dramatically increases, along with testicular blood flow. varicocele only rarely detected in boys less than 10 years. left sided varicocle found in 15% of healthy young men.incontrast, the incidence in sub fertile men approaches 40% bilateral varicocele is uncommon in healthy men (less than 10%) but palpated in 20% in sub fertile men. in-general varicocele don't spontaneously regress. an accurate physical examination remain the corner stone of varicocele diagnosis.

several anatomic features contribute to the predominance of left sided varicocele is the left intrnal spermatic vein longer than the right and it typically joins the left renal vein at a right angle.as result of this character higher venous pressures fair transmited to the left spermatic vein and result in reterograde reflux of blood.

varicocle are associated with testicular atrophhy and varicocle correction can reverse atrophy in adolececnt. there is strong evidence affect semen quality it can cause abnormalties in concentration, motility and morphology.main defect is the motility.

indication of varicocelectomy:

1. Large varicoceles in adolescents

2. Childhood varicocele with testicular atrophy

3. Varicoceles with elevated FSH values, or low testosterone levels

4. Varicoceles with scrotal pain

5. Cosmetic indication

6. Male infertility with pathological semen analysis and varicocele

Study Timeline

• Study First Submitted: 2017-08-25
• Status Verified: 2017-09
• Study First Submitted QC: 2017-09-11
• Last Update Submitted: 2017-09-11
• Study First Posted: 2017-09-13
• Last Update Posted: 2017-09-13
• Study Start: 2017-10-15
• Primary Completion: 2018-10-15
• Study Completion: 2018-10-15

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 32

Inclusion Criteria

• age more than 19 years old
• primary varicocele

Read More

Exclusion Criteria

• secondary varicocele recurrent varicocele age less than 19 years

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
high inguinal approch	High inguinal Varicocelectomy	Patients undergoing high inguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded
subinguinal approch	Subinguinal varicocelectomy	Patients undergoing subinguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded

Primary Outcome Measures

Name	Time	Method
Semen analysis	3months	Motility morphology concentration

Trial Locations

Locations (1)

Assuit Medical School; 🇪🇬 Assiut, Assuit, Egypt