Screening for Atrial Fibrillation in Elderly Women Older Than 70 Years
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Anticoagulant use for prevention of stroke
研究概览
简要总结
Screening for Atrial Fibrillation in Elderly Women (SAFE-W) is a pilot study evaluating the prevalence of atrial fibrillation (Afib) in a rapidly aging segment of the population. Studies have shown that women with Afib are more likely to be symptomatic, have increased mortality from stroke resulting from Afib, and are less likely to receive treatment for Afib. University of Maryland Department of Neurology and Vascular Neurology are recruiting women older than 70 years of age to participate in the study.
详细描述
Atrial fibrillation or irregular heart beat is seen in 1/3rd of patients that present with stroke. Atrial fibrillation is being increasingly seen in women older than 70 as women are likely to live longer. Women are more likely to die from atrial fibrillation related stroke and are more likely to have symptoms from uncontrolled atrial fibrillation. They are also less likely to be treated with blood thinners to prevent stroke. This section of the population has been underrepresented in other studies on atrial fibrillation and the aim of this study is to proactively screen women older than 70 who are at risk for atrial fibrillation by using a wearable cardiac monitor.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 100 Years（Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •No previous diagnosis of atrial fibrillation
- •Age ≥70 years
- •CHA2DS2-VASc score ≥4
排除标准
- •Life expectancy < 2 years
- •Dementia or other neurologic condition which would make outpatient follow-up difficult
- •CHA2DS2-VASc score ≤3
- •Any compliance issues - such as heavy alcohol/drug use that would impede follow up.
研究组 & 干预措施
Intervention arm
Women older than 70 who would wear the Zio patch for 2 weeks
干预措施: Wearable cardiac monitor -Zio patch (Device)
结局指标
主要结局
Anticoagulant use for prevention of stroke
时间窗: 2 years
Rate of anticoagulant prescription
Rate of detection of atrial fibrillation
时间窗: 1 year
Percentage of women older than 70 found to have atrial fibrillation one year from enrollment
次要结局
- Device adherence(1 year)
研究者
Prachi Mehndiratta
Assistant Professor
University of Maryland, Baltimore