Feasibility Trial Using an Insulin Dosing Calculator for Patients With Type 2 Diabetes Mellitus on Hospital Admission
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 5
- 主要终点
- Clinical significant hypoglycemia
研究概览
简要总结
The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission. The main questions it aims to answer are:
- Whether using this calculator leads to no excessive hypoglycemia?
- Whether using this calculator leads to a decrease of hyperglycemia?
Participants will receive initial insulin doses by the calculator on hospital admission, and the rest of care will follow standard of care. Participants will be compared with patients in the UW observational cohort who received initial insulin doses by standard of care.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are admitted to University of Washington Medical Centers
- •With history of type 2 and/or steroid-induced diabetes mellitus
- •Receiving insulin therapy prior to admission
排除标准
- •Patients who are admitted to ICU or obstetrics ward
- •Patients who are admitted for elective surgery or procedure
- •Patients who present with diabetic ketone acidosis, hyperosmolar hyperglycemic state or require intravenous insulin infusion
- •Patients who have no meal intake for 24 hours prior to admission, or planned nothing per oral (NPO) during the first 24 hours after admission
- •Patients who report low appetite (25% or less) on admission or have a significantly decreased level of consciousness that study team does not think they are going to eat right after admission
- •Patients who receive enteral feeding after admission
- •Patients who develop severe acute kidney injury needing dialysis therapy
研究组 & 干预措施
Initial insulin dosing calculator
干预措施: Initial insulin dosing calculator (Other)
Observational cohort
Historical patients who received initial insulin doses by standard of care
结局指标
主要结局
Clinical significant hypoglycemia
时间窗: During the first 48 hours after admission
Participates who develop blood glucose concentration lower than 54 mg/dL
Clinical Significant Hypoglycemia
时间窗: During the first 48 hours after admission
Participates developed blood glucose concentration lower than 54 mg/dL
次要结局
- Mean blood glucose concentration (mg/dL)(During the first 24 hours after admission)
- Hypoglycemia lower than 70 mg/dL(During the first 48 hours after admission)
- Clinical significant hyperglycemia(During the first 48 hours after admission)
- Mean Blood Glucose Concentration (mg/dL)(During the first 24 hours after admission)
- Clinical Significant Hyperglycemia(During the first 48 hours after admission)
- Hypoglycemia Lower Than 70 mg/dL(During the first 48 hours after admission)
研究者
Hou-Hsien Chiang
Clinician researcher
University of Washington