Pulmonary Rehabilitation in COPD: Effects of Two Aerobic Exercise Intensity in Patient-centered Outcomes - a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 主要终点
- Health-related quality-of-life measured by the St.George's respiratory questionnaire
研究概览
简要总结
Trial design: An equivalence/non-inferiority randomized controlled trial with parallel group design studied the effect of two aerobic exercise-training intensities in COPD patient-centered outcomes. Methods: Thirty-four COPD clinically stable patients stratified from mild to very severe GOLD stages, were blinded to 60 or 80%Wmax aerobic exercise training intensity in an outpatient pulmonary rehabilitation program, between 2009-2010. Outcomes were assessed with St.George's respiratory questionnaire (primary outcome), Mahler dyspnea index, London Chest activity of daily living scale, 6-minute walk, constant load and incremental exercise tests. Patient's allocation sequence was computer-generated, with consignment in a safe deposit box.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinically stable COPD
- •FEV1/FVC < 70%
- •Exercise training medical referral
排除标准
- •Unable to attend 3-times/week program
- •Infectious disease
- •Metastatic cancer
- •Unstable heart disease
- •Neuromusculoskeletal disorder
- •Cognitive or psychiatric disorder
结局指标
主要结局
Health-related quality-of-life measured by the St.George's respiratory questionnaire
时间窗: 8 weeks (20 sessions)
次要结局
- Symptoms control measured by the Mahler dyspnea index(8 weeks (20 sessions))
- Exercise Tolerance(8 weeks (20 sessions))