Unhealthy Alcohol Drinking and Anesthetic Requirement in Women

Not Applicable

Completed

• Conditions: General Anesthesia

• Registration Number: NCT00741507
• Lead Sponsor: Nanjing Medical University

Brief Summary

Unhealthy alcohol drinking is negatively influencing health of people and costing a large number of annual finance via "secondhand" effects. Additionally, unhealthy alcohol use covers a spectrum that is associated with varying degrees of risk to health. The investigators hypothesized that unhealthy alcohol drinking resulted in significant increase in anesthetic requirement during general anesthesia. This investigation would clarify the association between unhealthy alcohol use and the intraoperative consumption of anesthetics, and provide clinical evidence for preoperative assessment with respect to the alcohol drinking habit.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2008-08-20
• Study First Submitted QC: 2008-08-25
• Study First Posted: 2008-08-26
• Study Start: 2008-09
• Status Verified: 2009-07
• Primary Completion: 2009-07
• Study Completion: 2009-07
• Last Update Submitted: 2009-07-14
• Last Update Posted: 2009-07-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

• ASA physical status I-II
• Chinese
• 19-45yr
• Undergoing general anesthesia

Exclusion Criteria

• A history of the use of centrally-acting drugs of any sort, chronic pain and psychiatric diseases records.
• Participants younger than 18yr，older than 45yr or pregnancy was eliminated.
• Those who were not willing to or could not finish the whole study at any time.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Anesthetic requirements	10 min after completion of operation

Secondary Outcome Measures

Name	Time	Method
Odds Ratio of alcohol use and the consumption of anesthetics	1 day after completion of study
Side effects	30 min after completion of the study
Bispectral Index (BIS) value	0, 5, 10, 20, 30, 45, 60, 90 min after anesthesia
Economic assessment	1 day after operation

Trial Locations

Locations (1)

Nanjing Maternal and Child Health Care Hospital; 🇨🇳 Nanjing, Jiangsu, China