Relationship Between Performance Measurement of Intraoperative Mean Arterial Pressure and Mortality in Patients Undergoing Cardiac Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Blood Pressure
- Sponsor
- Seoul National University Hospital
- Enrollment
- 1300
- Locations
- 1
- Primary Endpoint
- Mortality
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This study aimed to evaluate the relationship between the perioperative blood pressure and postoperative mortality after cardiac surgery using performance measurement (PM) of mean arterial pressure (MAP).
Detailed Description
The authors conducted a retrospective cohort study of adult patients who underwent cardiac surgery requiring cardiopulmonary bypass (CPB). Median performance error (MDPE), median absolute performance error (MDAPE), and wobble of MAP were calculated using preoperative MAP as the reference value, and MBPs before, during and after the bypass as measured values. Univariable and multivariable logistic regression analyses were performed using PM parameters to predict in-hospital mortality. Survival after cardiac surgery was compared using the Cox proportional hazard model. Predictability of PM was assessed using the area under the receiver-operating characteristic curve (AUROC).
Investigators
Youn Joung Cho, MD
Clinical assistant professor
Seoul National University Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients undergoing cardiac surgery with cardiopulmonary bypass between 2013 and 2016 at Seoul National University Hospital.
Exclusion Criteria
- •Patients without information on preoperative blood pressure or mortality.
Outcomes
Primary Outcomes
Mortality
Time Frame: through study completion, average 3 years
mortality after cardiac surgery