Randomised Clinical Trial on the Short-Term Anti-plaque Effect of Cymenol Mouthwash Analysed Using Dentius Deep Plaque Software
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Change in the plaque area: 4 days vs 8 days
研究概览
简要总结
The objective of this project was to investigate the short-term in situ anti-plaque effect of cymenol, using the Dentius Deep Plaque software
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Placebo
Participants rinsed 10 ml of placebo mouthwash for a period of 60 seconds, three times a day with an interval of 7-9 hours in between, for 4 days (period 1)
干预措施: Placebo Mouthwash (Drug)
Cymenol (test)
Participants applied a 10 ml rinse of 0.1% cymenol mouthwash for a period of 60 seconds, three times a day with a 7-9 hour interval in between, for 4 days (period 1) and 4 days more (period 2)
干预措施: Cymenol mouthwash (Drug)
结局指标
主要结局
Change in the plaque area: 4 days vs 8 days
时间窗: 4 days, 8 days
Change in the percentage of the tooth surface with dental plaque: 4 days vs 8 days
Change in the plaque area: baseline vs 8 days
时间窗: Baseline, 8 days
Change in the percentage of the tooth surface with dental plaque: baseline vs 8 days
Change in the plaque area: baseline vs 4 days
时间窗: Baseline, 4 days
Change in the percentage of the tooth surface with dental plaque:baseline vs 4 days
Change in the growth rate of dental plaque area: baseline vs 4 days
时间窗: Baseline, 4 days
Change in the growth rate of dental plaque area (percentage area/hour): baseline vs 4 days
Change in the growth rate of dental plaque area: baseline vs 8 days
时间窗: Baseline, 8 days
Change in the growth rate of dental plaque area (percentage area/hour): baseline vs 8 days
Change in the growth rate of dental plaque area: 4 days vs 8 days
时间窗: 4 days vs 8 days
Change in the growth rate of dental plaque area (percentage area/hour): 4 days vs 8 days
次要结局
未报告次要终点
研究者
Inmaculada Tomás
Professor
University of Santiago de Compostela